Log In via Athens
Pediatric Only |
Images & Videos Only
Principles of Critical Care, 3e
Part V. Infectious Disorders
Chapter 52. Bacterial Infections of the Central Nervous System
Allan R. Tunkel, W. Michael Scheld
central nervous system infection.
Bacterial infections of the central nervous system (CNS) are frequently devastating. The brain possesses several defense mechanisms (e.g., intact cranium and blood-brain barrier) to prevent entry of bacterial species; but once microorganisms have gained entry to the CNS, host defense mechanisms are inadequate to control the infection. Antimicrobial therapy is limited by the poor penetration of many agents into the CNS and by the ability of antibiotics to induce inflammation in the CNS via their bacteriolytic action, thereby contributing to brain damage. We review meningitis, brain abscess, subdural empyema, epidural abscess, and intracranial thrombophlebitis, with an emphasis on recent developments in diagnosis and therapy as they pertain to the care of the critically ill patient...."
The content above is only an excerpt. For full access, log into an existing user account below,
an annual subscription, or
a short-term subscription to the complete website.
Subscriber Log In:
Forgot your Username/Password?
Copyright © McGraw-Hill Global Education Holdings, LLC. All rights reserved.
. Any use is subject to the
Your IP address is 188.8.131.52