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Goodman & Gilman's Pharmacologic Basis of Therapeutics, 12e
Section I. General Principles
Chapter 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
Iain L. O. Buxton, Leslie Z. Benet
Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination: Introduction
drug absorption; drug distribution; drug excretion; drug metabolism; pharmacodynamics; pharmacokinetics.
In order to understand and control the therapeutic action of drugs in the human body, one must know how much drug will reach the site(s) of drug action and when this will occur. The absorption, distribution, metabolism (biotransformation), and elimination of drugs are the processes of
(Figure 21). Understanding and employing pharmacokinetic principles can increase the probability of therapeutic success and reduce the occurrence of adverse drug effects in the body...."
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